With the establishment of Manila as a Spanish trading port in 1571, one of the most important economic links in the early modern world was established. Spanish silver flowed from the mines of Potosí (in modern Bolivia) through Manila to Ming-dynasty China. The interplay between these two empires created a global financial system that linked far flung parts of the world in a way that mirrors the 20th century phenomenon that has become known as “globalization.” Guest Ashley Dean just completed her doctorate in history at Emory University examining the impacts of this pre-modern trans-Pacific linkage whose far-reaching impact touched nearly every part of the globe.